Genomics England is a company wholly owned by the UK Department of Health and Social Care, established to deliver the 100,000 Genomes Project and integrate genomic medicine into NHS routine care. It provides whole genome sequencing diagnostics, partners with the NHS for genomic healthcare, and offers a secure research environment with linked genomic and clinical data for scientific discovery. Its initiatives have advanced diagnoses for rare diseases and cancers, positioning it as a leader in national genomic infrastructure.