Founding Engineer.

About Us

At Prescience, we are building a new healthcare system run by a medical superintelligence.

The bitter lesson has shown us that general methods leveraging computation beat approaches built on hand-crafted human knowledge, every time. Healthcare has ignored this lesson more thoroughly than almost any other industry. Clinical guidelines, prior auth rules, actuarial tables, and care pathways are exactly the kind of human-engineered priors that get steamrolled once you have enough data and enough compute.

Is embedding LLMs into prior authorization software the best use of soon-to-be general intelligence run on a cluster in Abilene? We don't believe so. We sit at the intersection of the three things this moment requires: the technical depth to build frontier AI, the clinical fluency to actually enter the room, and the ambition to own and direct $6T of healthcare spending to ensure Americans don't die.

Prescience is a seed-stage company, most recently valued at $150M post-money. It was founded by Rishab and Aditya Jain, two brothers who have been doing AI research together since 2014. Aditya earned his M.D. from Harvard Medical School and forwent a career in medicine to build Prescience. Rishab was named one of TIME’s 25 Most Influential Teens at 13, took first place in Bioengineering at ISEF, and successfully exited two past businesses before leaving Harvard to co-found Prescience.

Why Prescience?

Prescience is a generational opportunity to rebuild American healthcare from first principles. We have rapid organic adoption from employers, patients, and providers. As AI capabilities improve and the network effects compound across our volume, our business becomes even more indomitable.

In a world with AGI, only three sectors of the economy matter: compute, entertainment, and healthcare. Prescience is building the generational healthcare company, and has massive upside for early believers.

The Role

Our number one priority is scaling to market demand. We are looking for individuals who are high horsepower, high throughput, and extreme resourcefulness to help us increase capacity and grow. We move fast and need to move faster.

The models will do most of the work; your job is to build everything that lets them: the data, harnesses and tools, and infra. This is a founding role with an unprecedented level of ownership and agency. You will pick problems, own them end to end, and ship to production.

Skills We’re Looking For

We’re hiring two, high-agency, full-stack founding engineers.

• Full-stack, end to end. TypeScript across the stack: React on the front, a modern backend framework, a relational database.
• Product taste. Shipped work that shows real decisions about layout, hierarchy, and user experience.
• Web automation. Playwright, Puppeteer, Selenium, or computer-use agents. Tell us about systems you've automated or hacked in the past.
• LLMs in production. Hands-on with structured extraction, classification, and agentic workflows; a practical grasp of prompt design, structured outputs, retrieval, and fine-tuning.
• Integration-heavy systems. You've stitched together many external APIs and designed clean ones of your own.
• A bias toward scripting your way out of repetitive work.

In a single month at Prescience you'll route millions of real dollars over banking rails, build computer-use and LLM agents that extract and automate online systems, scrape terabytes of messy data, integrate dozens of APIs together, and ship a user experience that a patient uses to get care. You'll also get to grow in ML capabilities working alongside our research team.

Compensation and Benefits

• A generous cash base.
• Founding-team equity.
• The best health insurance you've ever had.
• Uber vouchers, DoorDash, Equinox.